Cerulenin

• Catalog number
  1579-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2,3-Epoxy-4-oxo-7,10-dodecadienamide
• Description
  Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or downstream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).
• CAS Number
  17397-89-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₂H₁₇NO₃
• Molecular Weight
  223.3
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (20 mg/ml) or EtOH (20 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  A FAS inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD00077686
• PubChem CID
  272023
• PubChem CID Link
• SMILES
  CC=CCC=CCCC(=O)C1C(O1)C(=O)N
• InChi
  InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6, 10-11H,4,7-8H2,1H3,(H2,13,15)
• InChi Key
  GVEZIHKRYBHEFX-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cerulenin  
• Short name
  Cerulenin
• Alternative name
  Cerulenin

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