Human anti Sm Antigen

• Catalog number
  MBS315463
• Price
  Please ask
• Size
  2 mL

• Products_type
  Antibody
• Products_short_name
  [Sm (Smith) Antigen]
• Products_name_syn
  [Human Antibody to Sm (Smith) Antigen]
• Clonality
  Polyclonal
• Specificity
  Shows the Sm precipitate band when tested using double immunodiffusion against rabbit thymus extract. Specificity is verified by identity of precipitation with CDC-AF reference serum. Anti-RNP precipitant is also detected. Titer will vary with test system; however, undiluted antibody shows a strong Sm precipitate band. Exhibits no reactivity at a dilution of 1:100 when tested against purified SSB, Scl-70 and Jo-1 antigens in an ELISA system designed to detect all IgG subclasses. Anti-RNP and low levels of anti-SSA activity are detected in this ELISA system.
• Purity
  Single donor human plasma is delipidized and defibrinated. An immunoglobulin fraction is then precipitated and collected.
• Form
  Purified, Lyophilized Reconstitute with 2ml deionized water.
• Storage_stability
  Store at at or below 0 degrees Celsius. Avoid multiple freeze/thaw cycles.
• Tested_application
  Immunodiffusion, ELISA.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antigens are peptides or recombinant or native dependent on the production method.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  -
• Gene symbol
  SNRPE, SNRPF, SNRPG
• Short name
  anti Sm Antigen
• Technique
  antigen, anti, antibody to, antigenes
• Host
  Human plasma
• Species
  Human, Humans
• Alternative name
  H. sapiens antibody to Sm protein
• Alternative technique
  antigenes, antibodies

Gene info

• Identity
  HGNC:11161
• Gene
  SNRPE
• Long gene name
  small nuclear ribonucleoprotein polypeptide E
• Synonyms
  • Sm-E
• GenBank acession
  • M37716
• Locus
  1q32.1
• Discovery year
  1988-11-28
• Entrez gene record
  6635
• Pubmed identfication
  • 1835977
  • 2143747
• RefSeq identity
  • NM_003094
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000035985

Gene info

• Identity
  HGNC:11162
• Gene
  SNRPF
• Long gene name
  small nuclear ribonucleoprotein polypeptide F
• Synonyms
  • Sm-F
• GenBank acession
  • X85372
• Locus
  12q23.1
• Discovery year
  1990-06-13
• Entrez gene record
  6636
• Pubmed identfication
  • 7744013
• RefSeq identity
  • NM_003095
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000170351

Gene info

• Identity
  HGNC:11163
• Gene
  SNRPG
• Long gene name
  small nuclear ribonucleoprotein polypeptide G
• Synonyms
  • Sm-G
• GenBank acession
  • X85373
• Locus
  2p13.3
• Discovery year
  1990-06-13
• Entrez gene record
  6637
• Pubmed identfication
  • 7744013
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000129670

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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