MN64

• Catalog number
  B1127-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  2-[4-(1-methylethyl)phenyl]-4H-1-benzopyran-4-one
• Description
  MN64 is a potent and selective tankyrase (TNKS) inhibitor (IC₅₀ values of 6 and 72 nM for TNKS1 and TNKS2 respectively). It has no effect on PARP-1 or PARP-2 (IC₅₀ > 19 µM). Through its effects on TNKS, MN-64 inhibits signaling along the Wnt/β-catenin pathway in a cell-based reporter assay.
• CAS Number
  92831-11-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₆O₂
• Molecular Weight
  264.32
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml) or EtOH (>20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective tankyrase (TNKS) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00829158
• PubChem CID
  2802462
• PubChem CID Link
• SMILES
  CC(C)C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2
• InChi
  InChI=1S/C18H16O2/c1-12(2)13-7-9-14(10-8-13)18-11-16(19)15-5-3-4-6-17(15)20-18/h3-12H,1-2H3
• InChi Key
  PYTOHIUBXSJKQH-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  MN64  
• Short name
  MN64
• Alternative name
  MN64

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