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anti-Dnmt2 Antibody

anti-Dnmt2 Antibody is available 1 time from Biovision labs

3488-100 | anti-Dnmt2 Antibody size: Dnmt2 Antibody | 404.52 USD

Catalog number 3488-100
Supplier Biovision
Price 404.52 USD
Size Dnmt2 Antibody
1. Gene info
Identity 2977
Long gene name tRNA aspartic acid methyltransferase 1
Synonyms gene
  • DNMT2
Synonyms gene name
  • DNA (cytosine-5-)-methyltransferase 2
  • RNMT1
Synonyms name
  • tRNA (cytosine(38)-C(5))-methyltransferase
GenBank acession
  • AJ223333
Locus 10p13
Discovery year 1998-05-07
Entrez gene record 1787
Pubmed identfication
  • 9425235
  • 9763678
  • 16424344
RefSeq identity
  • NM_004412
  • Seven-beta-strand methyltransferase motif containing
Havana BLAST/BLAT OTTHUMG00000017745
Product images
    #0#.jpegDnmt2 Antibody
Target of this antibody: DNMT2
Alternative names of antibody target: Dnmt2 , TRDMT1 , RNMT1 , OTTHUMP00000045198 , cytosine-5-methyltransferase , EC
Background information: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse
Immunogene sequence: Synthetic peptides surrounding amino acid 42 and 364 of mouse Dnmt2
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot, Immunofluorescence
Recommended usage: Western blotting (0.5-4 µg/ml) and immunofluorescence. However, the optimal concentrations should be determined individually. The antibody recognizes 42 kDa Dnmt 2 of human and mouse origins. Mouse testes tissue lysate can be use as a positive control.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetDnmt2
Short name anti-Dnmt2 Antibody
Technique Antibody, anti
Alternative name antibody to-Dnmt2 (Antibody to)
Alternative technique antibodies
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anti-Dnmt2 Antibody | Technique alternative | 01012192387
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • Dnmt2
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