Cyclin A

• Catalog number
  GEN438286
• Price
  Please ask
• Size
  100ug

• Also known as
  Cyclin A
• Other names
  cyclin-A2; Cyclin-A2; cyclin-A2; cyclin A2; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CCNA2
• Gene name synonims
  N/A
• Other gene names
  CCNA2; CCNA2; CCN1; CCNA; CCN1; CCNA; Cyclin-A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a, kappa
• Clone
  E67
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Cow, African Green Monkey, Mink (Mustela).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)

• Gene target
  Cyclin  
• Gene symbol
  CCNQ, SCAPER, MNAT1
• Short name
  Cyclin A
• Alternative name
  Anti-Cyclin A

Gene info

• Identity
  HGNC:28434
• Gene
  CCNQ
• Long gene name
  cyclin Q
• Synonyms gene
  • FAM58A
• Synonyms gene name
  • family with sequence similarity 58, member A
  • family with sequence similarity 58 member A
• Synonyms
  • CycM
• Synonyms name
  • cyclin M
• GenBank acession
  • BC032121
• Locus
  Xq28
• Discovery year
  2005-05-19
• Entrez gene record
  92002
• Pubmed identfication
  • 18297069
  • 24218572
  • 27104747
• RefSeq identity
  • NM_152274
• Classification
  • Cyclins
• VEGA ID
  OTTHUMG00000024206

Gene info

• Identity
  HGNC:13081
• Gene
  SCAPER
• Long gene name
  S-phase cyclin A associated protein in the ER
• Synonyms gene
  • ZNF291
• Synonyms gene name
  • zinc finger protein 291
• Synonyms
  • Zfp291
• GenBank acession
  • AB040887
  • AF242528
• Locus
  15q24.3
• Discovery year
  2000-03-15
• Entrez gene record
  49855
• Pubmed identfication
  • 17698606
• RefSeq identity
  • NM_020843
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000172655

Gene info

• Identity
  HGNC:7181
• Gene
  MNAT1
• Long gene name
  MNAT1 component of CDK activating kinase
• Synonyms gene name
  • menage a trois 1 (CAK assembly factor)
  • menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
  • MNAT CDK-activating kinase assembly factor 1
  • MNAT1, CDK activating kinase assembly factor
• Synonyms
  • MAT1
  • RNF66
• Synonyms name
  • CDK-activating kinase assembly factor
• GenBank acession
  • X87843
• Locus
  14q23.1
• Discovery year
  1997-10-09
• Entrez gene record
  4331
• Pubmed identfication
  • 9465303
• RefSeq identity
  • NM_002431
• Classification
  • Nucleotide excision repair
  • CDK activating kinase complex
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000152340

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