Recombinant Rabbit Tumor Necrosis Factor α/TNF-α
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Catalog number
C082
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Price
Please ask
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Size
50ug
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Alternative names
Tumor Necrosis Factor, Cachectin, TNF-Alpha, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, TNF, TNFA, TNFSF2
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Description
Recombinant Rabbit Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Val77-Leu235 is expressed.
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Expression
E. coli
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Tag
tag free
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug)
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Accession
P04924
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TargetSequence
Val77-Leu235
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Shipping
Ambient
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Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH7.4.
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Note
For research use only.
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Additional description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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About
Rabbits are used for polyclonal antibody production by Bon Opus. Rabbit antibodies are very stable and can be stored for several days at room temperature. Bon Opus adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbol
TNF, TNFRSF1A, TNFRSF1B, LTBR
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Short name
Recombinant Rabbit Tumor Necrosis Factor α/TNF-α
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Technique
Recombinant, Rabbit, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
Rabbit, Rabbits
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Species
Rabbit
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Alternative name
Rec. production species: rabbit Tumor Necrosis Factor α/tumor necrosis factor-α
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Alternative technique
rec, rabbit-anti
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Alternative to gene target
tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Tissue
tumor
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Gene info
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Identity
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Gene
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Long gene name
tumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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