2-Methyl-5-hydroxytryptamine hydrochloride
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Catalog number2768-25
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Price:
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Size25 mg
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Alternative_name3-(2-aminoethyl)-2-methyl-1H-indol-5-ol hydrochloride; 2-Me-5HT
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Description2-Methyl-5-hydroxytryptamine is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). Recently, this has been used as one of the components of the chemical cocktails used for reprogramming of mouse somatic cells toward pluripotent cells in the absence of Oct4.
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CAS Number845861-49-6
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Structure AvailableY
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Salt FormNo
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Molecular FormulaC₁₁H₁₄N₂O.HCl
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Molecular Weight226.71
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Cell PermeableY
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Purity≥98% by HPLC
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SolubilitiesH₂O (>20 mg/ml)
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HandlingProtect from light and moisture
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Tag LineA 5-HT3 agonist
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Storage ConditionRT
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Shipping ConditionRT
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Shelf Life36 months
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PubChem CID11492320
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SMILESCC1=C(C2=C(N1)C=CC(=C2)O)CCN.Cl
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InChiInChI=1S/C11H14N2O.ClH/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7;/h2-3,6,13-14H,4-5,12H2,1H3;1H
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InChi KeyZNVRHQPXSBWLQP-UHFFFAOYSA-N
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MSDS AvailableYes
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Additional descriptionA methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
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Gene target
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Gene symbolMIR1302-5, PIRC23, PIRC22, PIRC20, PIRC21, HTR6, IGKV3OR2-5, IGHV2OR16-5, SNORD116-5, TGFB1I1
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Short name2-Methyl-5-hydroxytryptamine hydrochloride
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Alternative name2-Methyl-5-hydroxytryptamine hydrochloride
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Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-5
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 23
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 22
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 20
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 21
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene name5-hydroxytryptamine receptor 6
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Synonyms gene name
- 5-hydroxytryptamine (serotonin) receptor 6
- 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 5-hydroxytryptamine receptors, G protein-coupled
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 3/OR2-5 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 3/OR2-5
- immunoglobulin kappa variable 3/OR2-5 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 2/OR16-5 (non-functional)
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Synonyms gene name
- immunoglobulin heavy variable 2/OR16-5
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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Classification
- Immunoglobulin heavy (IGH) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-5
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nametransforming growth factor beta 1 induced transcript 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-03-23
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Entrez gene record
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Pubmed identfication
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Classification
- LIM domain containing
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VEGA ID