CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Mouse Monoclonal Antibody
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Products_type
Antibody
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Products_short_name
[CD30 / TNFRSF8]
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Products_name_syn
[CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)]
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Other_names
[tumor necrosis factor receptor superfamily member 8 isoform 1; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily member 8; TNF receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen: CD30]
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Products_gene_name
[TNFRSF8]
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Other_gene_names
[TNFRSF8; TNFRSF8; CD30; Ki-1; D1S166E; CD30; D1S166E]
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Clonality
Monoclonal
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Clone
[SPM609]
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Reactivity
Human
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Specificity
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
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Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stability
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_application
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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Properties
If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
For cells, cell lines and tissues in culture till half confluency.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
TNFRSF8
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Short name
CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg ) Mouse Monoclonal Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1, kappa
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Species
Mouse, Mouses
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Alternative name
CD30 / tumor necrosis factor receptor superfamily, member 8 (Hodgkin & Reed-Sternberg cellular detection labelled) Mouse monoclonal (antibody to-)
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Alternative technique
antibodies, murine
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 8, CD30 and D1S166E and Ki-1, TNFRSF8 and IDBG-90058 and ENSG00000120949 and 943, protein binding, Plasma membranes, Tnfrsf8 and IDBG-203323 and ENSMUSG00000028602 and 21941, TNFRSF8 and IDBG-632372 and ENSBTAG00000039937 and 614780
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Tissue
cell
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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