anti- CDK6 antibody

• Catalog number
  FNab01561
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Immunogen
  cyclin-dependent kinase 6
• Synonyms
  CDKN6
• Calculated MW
  37 kDa
• Uniprot ID
  Q00534
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab01561(CDK6 antibody) at dilution of 1:50
• Image4
  Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01561(CDK6 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDK6  
• Gene symbol
  CDK6, CDK6-AS1
• Short name
  anti- CDK6 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- CDK6 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1777
• Gene
  CDK6
• Long gene name
  cyclin dependent kinase 6
• Synonyms
  • PLSTIRE
• Locus
  7q21.2
• Discovery year
  1994-02-14
• Entrez gene record
  1021
• Pubmed identfication
  • 1639063
• Classification
  • Cyclin dependent kinases
• VEGA ID
  OTTHUMG00000131697
• Locus Specific Databases
  • LRG_991

Gene info

• Identity
  HGNC:40141
• Gene
  CDK6-AS1
• Long gene name
  CDK6 antisense RNA 1
• Synonyms
  • BALR-2
• Synonyms name
  • B-ALL associated long RNA-2
• Locus
  7q21.2
• Discovery year
  2019-07-24
• Entrez gene record
  101927497
• Pubmed identfication
  • 25681502
• RefSeq identity
  • NR_110086
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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