Kininogen, HMW, Human Plasma

• Catalog number
  7300-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight Kininogen, Williams-Fitzgerald-Flaujeac factor, BDK, KNG, Kininogen-1 heavy chain, T-kinin, Bradykinin, Lysyl-bradykinin, Kininogen-1 light chain, Low molecular weight growth-promoting factor
• Alternative_names
  Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight Kininogen, Williams-Fitzgerald-Flaujeac factor, BDK, KNG, Kininogen-1 heavy chain, T-kinin, Bradykinin, Lysyl-bradykinin, Kininogen-1 light chain, Low molecular weight growth-promoting factor
• Description
  A major extra-cellular cysteine proteinase inhibitor
• Recombinant
  No
• Source
  Human Plasma
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Molecular Weight
  120 kDa
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Appearance
  Frozen
• Physical form description
  Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI.
• Background Information
  HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Kininogen   HMW   Plasma  
• Gene symbol
  CFAP97, CSPG4
• Short name
  Kininogen, HMW, Plasma
• Species
  Human, Humans
• Alternative name
  Kininogen, HMW, H. sapiens Plasma

Gene info

• Identity
  HGNC:29276
• Gene
  CFAP97
• Long gene name
  cilia and flagella associated protein 97
• Synonyms gene
  • KIAA1430
• Synonyms gene name
  • KIAA1430
• Synonyms
  • DKFZp434F1728
  • hmw
• GenBank acession
  • AB037851
• Locus
  4q35.1
• Discovery year
  2004-04-21
• Entrez gene record
  57587
• Pubmed identfication
  • 10718198
  • 24554765
  • 26638075
• RefSeq identity
  • NM_020827
• Classification
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000160468

Gene info

• Identity
  HGNC:2466
• Gene
  CSPG4
• Long gene name
  chondroitin sulfate proteoglycan 4
• Synonyms gene name
  • chondroitin sulfate proteoglycan 4 (melanoma-associated)
• Synonyms
  • MCSPG
  • MEL-CSPG
  • MSK16
  • NG2
  • MCSP
  • HMW-MAA
  • CSPG4A
• Synonyms name
  • melanoma-associated chondroitin sulfate proteoglycan
• GenBank acession
  • X96753
  • AY359468
• Locus
  15q24.2
• Discovery year
  1997-11-28
• Entrez gene record
  1464
• Pubmed identfication
  • 8790396
  • 16407841
• RefSeq identity
  • NM_001897
• Classification
  • Proteoglycans
• VEGA ID
  OTTHUMG00000142836

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