TA-02

• Catalog number
  B1215-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  4-(2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine
• Description
  TA-02 is a potent inhibitor of p38 MAPK (IC₅₀ = 20 nM). It induces differentiation in cardiomyocytes from human embryonic stem cells after mesoderm induction.
• CAS Number
  1784751-19-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₁₃F₂N₃
• Molecular Weight
  333.33
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO(5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent p38 MAPK inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  91691130
• PubChem CID Link
• SMILES
  C1=CC=C(C(=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)F
• InChi
  InChI=1S/C20H13F2N3/c21-15-7-5-13(6-8-15)18-19(14-9-11-23-12-10-14)25-20(24-18)16-3-1-2-4-17(16)22/h1-12H,(H,24,25)
• InChi Key
  QIFJOFNVIVQRNJ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  TA-02  
• Gene symbol
  HCG4P2, PPTC7, KBTBD8, WDR36, LRRC8B, MT-TA, NFKBID, HCAR1
• Short name
  TA-02
• Alternative name
  TA-02

Gene info

• Identity
  HGNC:30979
• Gene
  HCG4P2
• Long gene name
  HLA complex group 4 pseudogene 2
• Synonyms
  • HCGIV-02
• Locus
  6p21.3
• Discovery year
  2003-12-16
• Entrez gene record
  387504

Gene info

• Identity
  HGNC:30695
• Gene
  PPTC7
• Long gene name
  protein phosphatase targeting COQ7
• Synonyms gene name
  • PTC7 protein phosphatase homolog (S. cerevisiae)
• Synonyms
  • TA-PP2C
• Synonyms name
  • T cell activation protein phosphatase 2C
• GenBank acession
  • AF385435
• Locus
  12q24.11
• Discovery year
  2006-02-27
• Entrez gene record
  160760
• Pubmed identfication
  • 15177553
  • 30267671
• RefSeq identity
  • NM_139283
• Classification
  • Protein phosphatases, Mg2+/Mn2+ dependent
• VEGA ID
  OTTHUMG00000169529

Gene info

• Identity
  HGNC:30691
• Gene
  KBTBD8
• Long gene name
  kelch repeat and BTB domain containing 8
• Synonyms gene name
  • kelch repeat and BTB (POZ) domain containing 8
• Synonyms
  • TA-KRP
  • KIAA1842
• Synonyms name
  • T-cell activation kelch repeat protein
• GenBank acession
  • AF385438
• Locus
  3p14.1
• Discovery year
  2005-08-22
• Entrez gene record
  84541
• Pubmed identfication
  • 11347906
• RefSeq identity
  • NM_032505
• Classification
  • BTB domain containing
• VEGA ID
  OTTHUMG00000158779

Gene info

• Identity
  HGNC:30696
• Gene
  WDR36
• Long gene name
  WD repeat domain 36
• Synonyms gene
  • GLC1G
• Synonyms gene name
  • glaucoma 1, open angle, G
• Synonyms
  • TA-WDRP
  • UTP21
• GenBank acession
  • AF385437
• Locus
  5q22.1
• Discovery year
  2004-03-16
• Entrez gene record
  134430
• Pubmed identfication
  • 15590835
  • 15677485
• RefSeq identity
  • NM_139281
• Classification
  • UTPb subcomplex
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000128790

Gene info

• Identity
  HGNC:30692
• Gene
  LRRC8B
• Long gene name
  leucine rich repeat containing 8 VRAC subunit B
• Synonyms gene name
  • leucine rich repeat containing 8 family member B
• Synonyms
  • TA-LRRP
  • KIAA0231
• Synonyms name
  • T cell activation leucine repeat rich protein
• GenBank acession
  • AF385436
• Locus
  1p22.2
• Discovery year
  2005-06-29
• Entrez gene record
  23507
• Pubmed identfication
  • 9039502
  • 24790029
• RefSeq identity
  • NM_015350
• Classification
  • Volume regulated anion channel subunits
• VEGA ID
  OTTHUMG00000010129

Gene info

• Identity
  HGNC:7475
• Gene
  MT-TA
• Long gene name
  mitochondrially encoded tRNA-Ala (GCN)
• Synonyms gene
  • MTTA
• Synonyms gene name
  • tRNA alanine
  • mitochondrially encoded tRNA alanine
• Synonyms
  • trnA
• Synonyms name
  • mitochondrially encoded transfer RNA alanine
• Locus
  mitochondria
• Discovery year
  1989-10-12
• Entrez gene record
  4553
• Pubmed identfication
  • 7219534
  • 25873012
• Classification
  • Mitochondrially encoded transfer RNAs

Gene info

• Identity
  HGNC:15671
• Gene
  NFKBID
• Long gene name
  NFKB inhibitor delta
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
• Synonyms
  • TA-NFKBH
  • IkappaBNS
  • IkBNS
• Synonyms name
  • NF-kappa-B inhibitor delta
• GenBank acession
  • AF385434
• Locus
  19q13.12
• Discovery year
  2008-04-10
• Entrez gene record
  84807
• Pubmed identfication
  • 30127089
• RefSeq identity
  • NM_032721
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000180760

Gene info

• Identity
  HGNC:4532
• Gene
  HCAR1
• Long gene name
  hydroxycarboxylic acid receptor 1
• Synonyms gene
  • GPR104
  • GPR81
• Synonyms gene name
  • G protein-coupled receptor 104
  • G protein-coupled receptor 81
• Synonyms
  • HCA1
  • FKSG80
  • TA-GPCR
  • LACR1
• Synonyms name
  • lactate receptor 1
• GenBank acession
  • AF411110
• Locus
  12q24.31
• Discovery year
  2000-01-20
• Entrez gene record
  27198
• Pubmed identfication
  • 11574155
  • 19047060
  • 18952058
  • 21454438
• Classification
  • Hydroxycarboxylic acid receptors

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