Alternative names of antibody target:
STR1 , MGC126102 , STMY1 , Transin-1 , MGC126102 , MGC126103 , MGC126104 , EC 126.96.36.199 , SL-1 , Matrix metalloproteinase
Proteins of the matrix metalloprotease (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling as well as disease processes such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
This antibody reacts with:
Human, mouse, rat, horse, rabbit
Synthetic peptide surrounding amino acid 465 of rat MMP-3
Formulation of this antibody:
0.5 mg/ml purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the MMP-3 of human, mouse, rat, horse, and rabbit origins. Reactivity to other species has not been tested. The antibody detects the 55 kDa full length and the 21 kDa cleavage fragment of MMP-3.