3,3'-Diindolylmethane
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Catalog number2150-1000
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PricePlease ask
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Size1 g
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Alternative_name3,3’-Methylenediindole; DIM
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DescriptionDiindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells. Recently, it has been shown that DIM induces apoptosis in ovarian cancer cells by inhibiting JAK2/STAT3.
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CAS Number1968-05-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₁₄N₂
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Molecular Weight246.31
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (25 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent inhibitor of cancer stem cells
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD00195766
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PubChem CID3071
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SMILESC1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43
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InChiInChI=1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
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InChi KeyVFTRKSBEFQDZKX-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short name3 3'-Diindolylmethane
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Alternative name3,3'-Diindolylmethane
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