CD8 alpha, beta (CD8 alpha, CD8a, CD8 alpha Chain, CD8 Antigen alpha Chain, CD8 Antigen alpha Polypeptide (p32), CD8 beta, CD8b, CD8 Antigen beta Polypeptide 1, CD8B1, Leu2 T Lymphocyte Antigen, Leu-2, Leu2, Ly3, LYT3, MAL, MGC119115, OKT8 T cell Antigen,
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Catalog number
GEN609729
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Price
Please ask
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Size
100 Tests
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Also known as
CD8 alpha, beta
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Other names
CD8 antigen alpha polypeptide; N/A; CD8 antigen alpha polypeptide; CD8 alpha chain; T-cell surface molecule; CD8 antigen, alpha polypeptide (p32); N/A; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CD8A; N/A; CD8; N/A
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Gene name synonims
CD8A; N/A; CD8; N/A
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Other gene names
CD8A; N/A; CD8; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
10B2014
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Host organism
Mouse (Mus musculus)
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Source organism
Feline
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Species reactivity
Feline; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes the feline homolog of human CD8. Specifically recognizes an epitope associated with the alpha/beta complex of the CD8 heterodimer (3). Does not react with human.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Purified
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Form Appearance
Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.
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Concentration
N/A
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Storage and shipping
May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
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Tested applications
Flow Cytometry (FC/FACS)
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Description
The CD8 alpha, beta (CD8 alpha, CD8a, CD8 alpha Chain, CD8 Antigen alpha Chain, CD8 Antigen alpha Polypeptide (p32), CD8 beta, CD8b, CD8 Antigen beta Polypeptide 1, CD8B1, Leu2 T Lymphocyte Antigen, Leu-2, Leu2, Ly3, LYT3, MAL, MGC119115, OKT8 T Antigen, is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. Cytotoxic T cells cluster differentiators for flow cytometry. This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity. For cells, cell lines and tissues in culture till half confluency.
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Gene target
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Gene symbol
CD8A, CD8B, TIRAP, MAL, MRTFA
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Short name
CD8 alpha, beta (CD8 alpha, CD8a, CD8 alpha Chain, CD8 Antigen alpha Chain, CD8 Antigen alpha Polypeptide (p32), CD8 beta, CD8b, CD8 Antigen beta Polypeptide 1, CD8B1, Leu2 T Lymphocyte Antigen, Leu-2, Leu2, Ly3, LYT3, MAL, MGC119115, OKT8 T Antigen,
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Technique
antigen, antigenes
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Alternative name
Anti-CD8 alpha, beta (CD8 alpha, CD8a, CD8 alpha Chain, CD8 Antigen alpha Chain, CD8 Antigen alpha Polypeptide (p32), CD8 beta, CD8b, CD8 Antigen beta Polypeptide 1, CD8B1, Leu2 T Lymphocyte Antigen, Leu-2, Leu2, Ly3, LYT3, MAL, MGC119115, OKT8 T cell Antigen,
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Alternative technique
antigenes
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Alternative to gene target
CD8a molecule, CD8 and Leu2 and MAL and p32, CD8A and IDBG-59987 and ENSG00000153563 and 925, protein homodimerization activity, Extracellular, Cd8a and IDBG-155582 and ENSMUSG00000053977 and 12525, CD8A and IDBG-634911 and ENSBTAG00000021141 and 281060
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Tissue
cell, lymphocyte
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Gene info
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Identity
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Gene
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Long gene name
CD8a molecule
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Synonyms gene
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Synonyms gene name
- CD8 antigen, alpha polypeptide (p32)
- T-cell surface glycoprotein CD8 alpha chain
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
CD8b molecule
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Synonyms gene
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Synonyms gene name
- CD8 antigen, beta polypeptide 1 (p37)
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Locus
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Discovery year
1989-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- V-set domain containing
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VEGA ID
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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