NKRF (NF-kappa-B-repressing Factor, NFkB-repressing Factor, Transcription Factor NRF, ITBA4 Protein, NRF, ITBA4)

• Catalog number
  MBS6010853
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• Gene
  NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory

• Gene target
  NKRF   NF-kappa-B-repressing   Factor   NFkB-repressing   Factor   Transcription   Factor   NRF   ITBA4   Protein   NRF   ITBA4  
• Gene symbol
  NKRF, NFYA, NFE4, NFE2, NFE2L2, SNRPB, NEFH, ORM2, NFKB1, INA
• Short name
  NKRF (NF-kappa-B-repressing Factor, NFkB-repressing Factor, Transcription Factor NRF, ITBA4 Protein, NRF, ITBA4)
• Alternative name
  NKRF (NF-kappa-B-repressing Factor, NFkB-repressing Factor, Transcription Factor NRF, ITBA4 Protein, NRF, ITBA4)

Gene info

• Identity
  HGNC:19374
• Gene
  NKRF
• Long gene name
  NFKB repressing factor
• Synonyms gene name
  • NF-kappaB repressing factor
• Synonyms
  • ITBA4
  • NRF
• GenBank acession
  • AJ011812
• Locus
  Xq24
• Discovery year
  2004-11-01
• Entrez gene record
  55922
• Pubmed identfication
  • 10562553
• RefSeq identity
  • NM_017544
• Classification
  • G-patch domain containing
• VEGA ID
  OTTHUMG00000022277
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:7804
• Gene
  NFYA
• Long gene name
  nuclear transcription factor Y subunit alpha
• Synonyms gene name
  • nuclear transcription factor Y, alpha
• Synonyms
  • HAP2
  • CBF-B
  • NF-YA
• Locus
  6p21.1
• Discovery year
  1991-11-08
• Entrez gene record
  4800
• Pubmed identfication
  • 1774067
  • 9612081
• VEGA ID
  OTTHUMG00000014669

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:7782
• Gene
  NFE2L2
• Long gene name
  NFE2 like bZIP transcription factor 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2)-like 2
  • nuclear factor, erythroid 2-like 2
  • nuclear factor, erythroid 2 like 2
• Synonyms
  • NRF2
  • NRF-2
• Synonyms name
  • NF-E2-related factor 2
• Locus
  2q31.2
• Discovery year
  1994-03-24
• Entrez gene record
  4780
• Pubmed identfication
  • 7937919
• RefSeq identity
  • NM_006164
• Classification
  • Basic leucine zipper proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133620

Gene info

• Identity
  HGNC:11153
• Gene
  SNRPB
• Long gene name
  small nuclear ribonucleoprotein polypeptides B and B1
• Synonyms gene
  • SNRPB1
• Synonyms
  • COD
  • SmB/SmB'
  • Sm-B/B'
  • snRNP-B
• Locus
  20p13
• Discovery year
  1988-11-28
• Entrez gene record
  6628
• Pubmed identfication
  • 1376292
• Classification
  • Small nucleolar RNA protein coding host genes
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000031694

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:8499
• Gene
  ORM2
• Long gene name
  orosomucoid 2
• Synonyms
  • AGP-B
  • AGP-B'
  • AGP2
• Synonyms name
  • alpha-1-acid glycoprotein, type 2
• Locus
  9q32
• Discovery year
  1991-03-11
• Entrez gene record
  5005
• Pubmed identfication
  • 4711474
  • 2970990
• RefSeq identity
  • NM_000608
• Classification
  • Lipocalins
• VEGA ID
  OTTHUMG00000021014

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:6057
• Gene
  INA
• Long gene name
  internexin neuronal intermediate filament protein alpha
• Synonyms gene
  • NEF5
• Synonyms gene name
  • internexin neuronal intermediate filament protein, alpha
• Synonyms
  • NF-66
• GenBank acession
  • S78296
• Locus
  10q24.33
• Discovery year
  1999-03-24
• Entrez gene record
  9118
• Pubmed identfication
  • 7769995
• RefSeq identity
  • NM_032727
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000018986

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