ALK 3'UTR Lenti-reporter-GFP Virus

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Ordering

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Technical file

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Notes

Designed for Research Use Only. Manufactured in Canada.
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Description

Lenti kit or vector with CMV or EF promotors for producing Lentivirus (lenti-, Latin for "slow") or lentiviral particles in 293t cells. Lentiviruses are characterized by a long incubation period and often Puro selected. Lentiviruses can deliver a significant amount of viral RNA into the DNA of the host cell and have the unique ability among retroviruses of being able to infect non-dividing cells. They are one of the most efficient methods of a gene delivery vector. The are packaged in HEK 293T cells to get the highest possible lentiviral titers of 108 IFU/ml. The Luc reporter is the expression of the firefly luciferase gene. Puro stands for puromicin selection.

Gene target

ALK 3'UTR reporter-GFP Virus
Gene symbol

ALK, ENPP7, TGFBR1, BMPR2
Short name

ALK 3'UTR -reporter-GFP Virus
Technique

lenti, Lentivectors and viral particles
Label

gfp
Species

Virus, Viruses
Alternative name

anaplastic lymphoma receptor tyrosine kinase 3'UTR lentiviral-detector-Green Fluorescent Virus
Alternative to gene target

anaplastic lymphoma receptor tyrosine kinase, CD246 and NBLST3, ALK and IDBG-42084 and ENSG00000171094 and 238, transferase activity, Plasma membranes, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642
Virus

lenti

Identity

HGNC:427
Gene

ALK
Long gene name

ALK receptor tyrosine kinase
Synonyms gene name
- anaplastic lymphoma kinase (Ki-1)
- anaplastic lymphoma receptor tyrosine kinase
Synonyms
- CD246
- ALK1
GenBank acession
- D45915
Locus

2p23.2-p23.1
Discovery year

1993-08-24
Entrez gene record

238
Pubmed identfication
- 8122112
RefSeq identity
- NM_004304
Classification
- Receptor tyrosine kinases
- CD molecules
VEGA ID

OTTHUMG00000152034
Locus Specific Databases
- LRG_488

Identity

HGNC:11772
Gene

TGFBR1
Long gene name

transforming growth factor beta receptor 1
Synonyms gene
- MSSE
- ESS1
Synonyms gene name
- multiple self-healing squamous epithelioma
- transforming growth factor beta receptor I
Synonyms
- ALK-5
- ACVRLK4
- ALK5
- TBRI
- TBR-i
Synonyms name
- activin A receptor type II-like kinase, 53kDa
Locus

9q22.33
Discovery year

1993-09-30
Entrez gene record

7046
Pubmed identfication
- 1319842
- 8530052
- 21358634
Classification
- Type 1 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000020353
Locus Specific Databases
- LOVD - Center for Medical Genetics, Ghent, Belgium

Identity

HGNC:1078
Gene

BMPR2
Long gene name

bone morphogenetic protein receptor type 2
Synonyms gene
- PPH1
Synonyms gene name
- primary pulmonary hypertension 1
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- bone morphogenetic protein receptor type II
Synonyms
- BRK-3
- T-ALK
- BMPR3
- BMPR-II
GenBank acession
- Z48923
Locus

2q33.1-q33.2
Discovery year

1997-03-19
Entrez gene record

659
Pubmed identfication
- 7791754
RefSeq identity
- NM_001204
Classification
- Type 2 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000133617
Locus Specific Databases
- LRG_712

Name

Artificial Gene Fusion
Concept

Scope note: The in vitro fusion of GENES by RECOMBINANT DNA techniques to analyze protein behavior or GENE EXPRESSION REGULATION, or to merge protein functions for specific medical or industrial uses.
Tree numbers
- E05.393.220.250
Qualifiers

drug effects, methods, radiation effects