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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
446-72-0
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Chemical s molecular weight
270.24
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Chemical s main applications
Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol
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Chemical s category
Inhibitors, Tyrosine Kinase Inhibitors
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Other name
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4',5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol;
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Chemical s formula
C15H10O5
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Physical properties
Light Tan to Light Yellow Solid
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Melting temperature
>277°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO, Methanol
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Stability conditions
Light Sensitive
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Storage
Amber Vial, -20°C Freezer, Under inert atmosphere
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