Baricitinib

• Catalog number
  2842-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  2-[1-Ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile; INCB 028050;LY 3009104;INCB028050;LY3009104;LY-3009104;INCB-028050
• Description
  Baricitinib is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and Chk2.
• CAS Number
  1187594-09-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₇N₇O₂S
• Molecular Weight
  371.42
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective JAK1 and JAK2 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  44205240
• PubChem CID Link
• SMILES
  CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
• InChi
  InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
• InChi Key
  XUZMWHLSFXCVMG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Baricitinib  
• Short name
  Baricitinib
• Alternative name
  Baricitinib

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