Synonyms Insulin-like growth factor binding protein-7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBPrP1)
Alternates names Insulin-like growth factor binding protein-7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBPrP1)
Taglines Plays a role in skeletal myogenesis by binding to IGF
NCBI Gene ID #. 3490
NCBI Gene Symbol IGFBP7
Gene Source Human
Accession # Q16270
Source E. Coli
Endotoxin Level<0.1 ng/μg of protein (
Activity (Specifications/test method) N/A
Biological activity N/A
Molecular Weight 26.4 kDa
Storage Temp. -20°C
Shipping Gel Pack
Shelf Life 1 year
Appearance Lyophilized powder
Physical form description Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Acetic Acid
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in acetic acid to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Additional source Recombinants or rec. proteins
Short name IGF-BP7, recombinant
Technique Recombinant, IGF
Alternative name IGF-BP7, H. sapiens recombinant
Alternative technique rec