DB07268

• Catalog number
  B1134-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  2-[[2-(3-hydroxyanilino)pyrimidin-4-yl]amino]benzamide
• Description
  DB07268 is a potent and selective JNK1 inhibitor with (IC₅₀ = 9 nM). DB07268 displays some degree of selectivity over quite a few kinases with the exceptions of CHK1, CK2, and PLK. Although DB07268 shows submicromolar potency against these three kinases, it still appears to exhibit at least 70- to 90-fold greater potency against JNK1 than CHK1, CK2, and PLK.
• CAS Number
  929007-72-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₅N₅O₂
• Molecular Weight
  321.34
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>3 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent JNK1 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  16058637
• PubChem CID Link
• SMILES
  C1=CC=C(C(=C1)C(=O)N)NC2=NC(=NC=C2)NC3=CC(=CC=C3)O
• InChi
  1S/C17H15N5O2/c18-16(24)13-6-1-2-7-14(13)21-15-8-9-19-17(22-15)20-11-4-3-5-12(23)10-11/h1-10,23H,(H2,18,24)(H2,19,20,21,22)
• InChi Key
  QHPKKGUGRGRSGA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  DB07268  
• Short name
  DB07268
• Alternative name
  DB07268

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