Batimastat (MMP Inhibitor)
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Catalog number1704-5
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PricePlease ask
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Size5 mg
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Alternative_nameBB-94
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DescriptionPotent, broad spectrum matrix metalloprotease (MMP) inhibitor (ICā ā values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human ovarian carcinoma xenografts in vivo.
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CAS Number130370-60-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaCāāHāāNāOāSā
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Molecular Weight477.64
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Cell PermeableYes
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Purityā„98% by HPLC
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SolubilitiesDMSO (100 mM)
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HandlingProtect from air and moisture
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Tag LineA broad spectrum matrix metalloprotease (MMP) inhibitor
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Storage Condition-20Ā°C
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Shipping ConditionGel pack
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Shelf Life12 months
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MDL NumberMFCD00866533
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PubChem CID5362422
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SMILESCC(C)CC(C(CSC1=CC=CS1)C(=O)NO)C(=O)NC(CC2=CC=CC=C2)C(=O)NC
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InChiInChI=1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1
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InChi KeyXFILPEOLDIKJHX-QYZOEREBSA-N
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MSDS AvailableYes
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitorsĀ areĀ proteinsĀ or receptor ligands or receptor antagonists that bind to anĀ enzyme receptorĀ and decreases itsĀ activity. Since blocking an enzyme's activity can kill a pathogenĀ or correct aĀ metabolicĀ imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors;Ā enzyme activator ligands or agonistsĀ bind to enzymes and increase theirĀ enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolMMP14, MMP24, MMP28, MMP17, MMP15, MMP25, MMP16
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Short nameBatimastat (MMP Inhibitor)
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Alternative nameBatimastat (MMP suppressor)
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Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 14
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Synonyms gene name
- matrix metalloproteinase 14 (membrane-inserted)
- matrix metallopeptidase 14 (membrane-inserted)
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-11-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 24
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Synonyms gene name
- matrix metalloproteinase 24 (membrane-inserted)
- matrix metallopeptidase 24 (membrane-inserted)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-08-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 28
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Synonyms gene name
- matrix metalloproteinase 28
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 17
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Synonyms gene name
- matrix metalloproteinase 17 (membrane-inserted)
- matrix metallopeptidase 17 (membrane-inserted)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 15
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Synonyms gene name
- matrix metalloproteinase 15 (membrane-inserted)
- matrix metallopeptidase 15 (membrane-inserted)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 25
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Synonyms gene
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Synonyms gene name
- matrix metalloproteinase 25
- matrix metallopeptidase-like 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-12-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 16
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Synonyms gene
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Synonyms gene name
- matrix metalloproteinase 16 (membrane-inserted)
- chromosome 8 open reading frame 57
- matrix metallopeptidase 16 (membrane-inserted)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-13
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Entrez gene record
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Pubmed identfication
-
RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID