Spautin-1

• Catalog number
  2037-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  6-Fluoro-N-(4-fluorobenzyl)quinozaline-4-amine
• Description
  Cell-permeable. A specific and potent autophagy inhibitor in mammalian cells. It promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin specific peptidases, USP10 and USP13, that target the Beclin1 subunit of Vps34 complexes. Spautin-1 blocks the prosurvival autophagy pathway in cancer cells.
• CAS Number
  1262888-28-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₁₁F₂N₃
• Molecular Weight
  271.26
• Cell Permeable
  No
• Purity
  ≥97% by HPLC
• Solubilities
  DMSO (~ 100 mM)
• Handling
  Protect from air and light
• Tag Line
  An USP10 and USP13 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• SMILES
  N/A
• InChi
  N/A
• InChi Key
  N/A
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Spautin-1  
• Short name
  Spautin-1
• Alternative name
  Spautin-1

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