STF-31

• Catalog number
  9585-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide
• Description
  STF-31 is a potent glucose transporter 1 (GLUT1) inhibitor (IC₅₀ = ~ 1 µM). It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress GLUT1. Recently, STF-31 has been shown to inhibit the enzyme activity of nicotinamide phosphoribosyltransferase (NAMPT) in biochemical assay in vitro.
• CAS Number
  724741-75-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₅N₃O₃S
• Molecular Weight
  423.53
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>30mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent glucose transporter 1 (GLUT1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD04153828
• PubChem CID
  984333
• PubChem CID Link
• SMILES
  CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NCC2=CC=C(C=C2)C(=O)NC3=CN=CC=C3
• InChi
  InChI=1S/C23H25N3O3S/c1-23(2,3)19-10-12-21(13-11-19)30(28,29)25-15-17-6-8-18(9-7-17)22(27)26-20-5-4-14-24-16-20/h4-14,16,25H,15H2,1-3H3,(H,26,27)
• InChi Key
  NGQPRVWTFNBUHA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  STF-31  
• Gene symbol
  SNORD114-31, SNORD115-31, ERVK-31, IGKV3-31, IGLV3-31, RNVU1-31, IGKV3D-31, IL31, OR1D5, RNU6-31P
• Short name
  STF-31
• Alternative name
  STF-31

Gene info

• Identity
  HGNC:33019
• Gene
  SNORD114-31
• Long gene name
  small nucleolar RNA, C/D box 114-31
• Synonyms
  • 14q(II-31)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767612
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003224.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33050
• Gene
  SNORD115-31
• Long gene name
  small nucleolar RNA, C/D box 115-31
• Synonyms
  • HBII-52-31
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033805
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003346.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:51379
• Gene
  ERVK-31
• Long gene name
  endogenous retrovirus group K member 31
• Synonyms gene name
  • endogenous retrovirus group K, member 31
• GenBank acession
  • LN624404
• Locus
  5q15
• Discovery year
  2015-05-14
• Pubmed identfication
  • 25750667

Gene info

• Identity
  HGNC:5819
• Gene
  IGKV3-31
• Long gene name
  immunoglobulin kappa variable 3-31 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 3-31
  • immunoglobulin kappa variable 3-31 pseudogene
• GenBank acession
  • X71883
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28910
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151688

Gene info

• Identity
  HGNC:5913
• Gene
  IGLV3-31
• Long gene name
  immunoglobulin lambda variable 3-31 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable 3-31
  • immunoglobulin lambda variable 3-31 pseudogene
• GenBank acession
  • X97469
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28788
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151179

Gene info

• Identity
  HGNC:54448
• Gene
  RNVU1-31
• Long gene name
  RNA, variant U1 small nuclear 31
• Locus
  1q21.1
• Discovery year
  2019-07-25
• Classification
  • Variant U1 small nuclear RNAs

Gene info

• Identity
  HGNC:5827
• Gene
  IGKV3D-31
• Long gene name
  immunoglobulin kappa variable 3D-31 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 3D-31
  • immunoglobulin kappa variable 3D-31 pseudogene
• GenBank acession
  • X71896
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28872
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151612

Gene info

• Identity
  HGNC:19372
• Gene
  IL31
• Long gene name
  interleukin 31
• Synonyms
  • IL-31
• GenBank acession
  • AY499343
• Locus
  12q24.31
• Discovery year
  2003-11-06
• Entrez gene record
  386653
• Pubmed identfication
  • 15184896
• RefSeq identity
  • NM_001014336
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000168916

Gene info

• Identity
  HGNC:8186
• Gene
  OR1D5
• Long gene name
  olfactory receptor family 1 subfamily D member 5
• Synonyms gene name
  • olfactory receptor, family 1, subfamily D, member 5
• Synonyms
  • OR17-31
• GenBank acession
  • AF087923
• Locus
  17p13.3
• Discovery year
  1998-09-14
• Entrez gene record
  8386
• Pubmed identfication
  • 10673334
• RefSeq identity
  • NM_014566
• Classification
  • Olfactory receptors, family 1
• VEGA ID
  OTTHUMG00000177676

Gene info

• Identity
  HGNC:34250
• Gene
  RNU6-31P
• Long gene name
  RNA, U6 small nuclear 31, pseudogene
• Synonyms gene
  • RNU6-31
• Synonyms gene name
  • RNA, U6 small nuclear 31
• Locus
  2q33.1
• Discovery year
  2008-06-10
• Entrez gene record
  100873740
• RefSeq identity
  • NR_046482

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