TSC2 Antibody

• Catalog number
  3962-200
• Price
  Please ask
• Size
  200 µg

• Antibody Target
  TSC2
• Target Alternative Name
  anti-TSC2, Tuberin, Tuberous sclerosis 2 protein homolog
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 1548 of rat TSC2
• Accession
  P49816.
• Gene Id
  24855
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  0.5 mg/ml affinity purified rabbit anti-TSC2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Jurkat (Induced and Uninduced), Rat kidney, 3T3 cell lysates
• Application And Usages
  The antibody can be used for Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 3962BP-50) is available separately.
• Description
  TSC2 is important in regulating cell proliferation and tumor development. Mutations in either the TSC1 or TSC2 tumor suppressor genes caused tuberous sclerosis complex (TSC), an autosomal dominant tumor syndrome. Tuberin is a product of the TSC2 tumor suppressor gene. Tuberin form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR).
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TSC2  
• Gene symbol
  TSC2
• Short name
  TSC2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  tuberous sclerosis 2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  tuberous sclerosis 2, LAM and PPP1R160 and TSC4, TSC2 and IDBG-9819 and ENSG00000103197 and 7249, 14-3-3 protein binding, nuclei, Tsc2 and IDBG-147651 and ENSMUSG00000002496 and 22084, TSC2 and IDBG-635000 and ENSBTAG00000020617 and 504985

Gene info

• Identity
  HGNC:12363
• Gene
  TSC2
• Long gene name
  TSC complex subunit 2
• Synonyms gene
  • TSC4
• Synonyms gene name
  • tuberous sclerosis 2
• Synonyms
  • tuberin
  • LAM
  • PPP1R160
• Synonyms name
  • protein phosphatase 1, regulatory subunit 160
• GenBank acession
  • AB014460
• Locus
  16p13.3
• Discovery year
  1989-05-25
• Entrez gene record
  7249
• Pubmed identfication
  • 1303246
  • 7558029
• RefSeq identity
  • NM_000548
• Classification
  • TSC complex
  • Armadillo like helical domain containing
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000128745
• Locus Specific Databases
  • TSC2 Mutation Database
  • Global Variome shared LOVD
  • LRG_487

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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