Anti-Calnexin Antibody (CANX/1541)

• Catalog number
  A1461-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  CANX
• Target Alternative Name
  Calnexin; CANX; CNX; IP90; Major histocompatibility complex class I antigen-binding protein p88; P90
• Antibody Type
  Monoclonal
• Clone
  CANX/1541
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant N-terminal fragment of human Calnexin protein
• Accession
  P27824
• Gene Id
  821
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 10 mM PBS with 0.05% BSA & 0.05% azide
• Purification
  Protein A/G purification
• Application
  FC, IF, IHC, WB
• Positive Control
  IHC: human Renal Cell Carcinoma, human Small Intestinal Carcinoma
• Application And Usages
  FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, WB: 0.5-1ug/ml, IHC: 0.5-1 ug/ml
• Description
  It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Calnexin   CANX/1541  
• Gene symbol
  CANX
• Short name
  Anti-Calnexin Antibody (CANX/1541)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG2b, kappa
• Alternative name
  Antibody toCalnexin (antibody to-) (CANX/1541)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1473
• Gene
  CANX
• Long gene name
  calnexin
• Synonyms
  • CNX
  • IP90
  • P90
• Synonyms name
  • major histocompatibility complex class I antigen-binding protein p88
• GenBank acession
  • L18887
• Locus
  5q35.3
• Discovery year
  1993-07-12
• Entrez gene record
  821
• Pubmed identfication
  • 1326756
  • 8136357
• RefSeq identity
  • NM_001024649
• VEGA ID
  OTTHUMG00000130910

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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