Evofosamide

• Catalog number
  B1912-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  Phosphorodiamidic acid, N,N'-bis(2-bromoethyl)-, (1-methyl-2-nitro-1H-imidazol-5-yl)methyl ester; TH302; TH-302
• Description
  Evofosfamide (TH-302) is an anticancer agent that is a hypoxia-activated prodrug that is created by linking the hypoxia-seeking 2-nitroimidazole moiety to the cytotoxic bromo-isophosphoramide mustard (Br-IPM). When evofosfamide is delivered to hypoxic regions of tumors, the DNA cross-linking toxin, Br-IPM, is released leading to cell death.
• CAS Number
  918633-87-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₉H₁₆Br₂N₅O₄P
• Molecular Weight
  449.04
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11984561
• PubChem CID Link
• SMILES
  CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr
• InChi
  InChI=1S/C9H16Br2N5O4P/c1-15-8(6-12-9(15)16(17)18)7-20-21(19,13-4-2-10)14-5-3-11/h6H,2-5,7H2,1H3,(H2,13,14,19)
• InChi Key
  UGJWRPJDTDGERK-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Evofosamide  
• Short name
  Evofosamide
• Alternative name
  Evofosamide

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