MyoGEF Antibody, ALEXA FLUOR 350

• Catalog number
  bs-7756R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  MyoGEF Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-MyoGEF PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MyoGEF
• Specificity
  This is a highly specific antibody against MyoGEF.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MyoGEF
• Gene ID Number
  55200
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  Myosin interacting guanine nucleotide exchange factor; PH domain containing family G member 6; Pleckstrin homology domain containing family G with RhoGef domain member 6; Pleckstrin homology domain-containing family G member 6; PLEKHG6；PKHG6_HUMAN。
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  MyoGEF  
• Gene symbol
  PLEKHG6
• Short name
  Anti-MyoGEF
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  MyoGEF Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25562
• Gene
  PLEKHG6
• Long gene name
  pleckstrin homology and RhoGEF domain containing G6
• Synonyms gene name
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 6
• Synonyms
  • FLJ10665
  • MYOGEF
• Synonyms name
  • myosin II interacting GEF
• GenBank acession
  • AK001527
• Locus
  12p13.31
• Discovery year
  2005-05-23
• Entrez gene record
  55200
• Pubmed identfication
  • 16721066
  • 17881735
• RefSeq identity
  • NM_018173
• Classification
  • Pleckstrin homology domain containing
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000168266

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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