Anti-GMP Synthase (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-13459R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  GMP Synthase
• Specificity
  This antibody reacts specifically with GMP Synthase
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human GMP Synthase
• Gene ID
  8833
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008].
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  GMPS; Glutamine amidotransferase; GMP synthase [glutamine hydrolyzing]; GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Gmps; GUAA_HUMAN; Guanine monphosphate synthetase; MLL/GMPS fusion protein.
• Also known as
  GMP Synthase Polyclonal Antibody
• Other name
  Anti-GMP Synthase Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  GMP   Synthase  
• Gene symbol
  NKG7, NT5C2
• Short name
  Anti-GMP Synthase
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  GMP Synthase Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:7830
• Gene
  NKG7
• Long gene name
  natural killer cell granule protein 7
• Synonyms gene name
  • natural killer cell group 7 sequence
• Synonyms
  • GIG1
  • GMP-17
• Synonyms name
  • granule membrane protein 17
• Locus
  19q13.41
• Discovery year
  1993-12-15
• Entrez gene record
  4818
• Pubmed identfication
  • 8458737
• RefSeq identity
  • NM_005601
• VEGA ID
  OTTHUMG00000182898

Gene info

• Identity
  HGNC:8022
• Gene
  NT5C2
• Long gene name
  5'-nucleotidase, cytosolic II
• Synonyms gene
  • NT5B
  • SPG45
• Synonyms gene name
  • 5'-nucleotidase (purine), cytosolic type B
  • spastic paraplegia 45 (autosomal recessive)
• Synonyms
  • PNT5
  • GMP
  • cN-II
  • SPG65
• Synonyms name
  • purine 5' nucleotidase
• GenBank acession
  • D38524
• Locus
  10q24.32-q24.33
• Discovery year
  2000-06-16
• Entrez gene record
  22978
• Pubmed identfication
  • 7999131
  • 24482476
  • 28327087
• RefSeq identity
  • NM_012229
• Classification
  • 5'-nucleotidases
• VEGA ID
  OTTHUMG00000018981

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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