anti-Connexin Antibody

• Catalog number
  50-200
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002; Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).
• Gene names
  Cx43, Cxn-43, Connexin-43, Cx43
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Purified
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Peptide corresponding to amino acid residues from the C-terminal region of rat connexin43.
• Immuno application
  Western Blot
• Antibody advice
  The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will also work with chicken, dog, finch, human, mouse, non-human primate, sheep, Xenopus and zebra fish tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
• Suspention pH azide
  100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
• Keep at
  Connexin antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
• Works with
  Human, Mouse, Rat, Dog, Zebrafish, Sheep, Chicken, Xenopus
• Omim nr
  117708
• Ncbi nr
  P08050
• KDa
  43
• Vial with antibody
  in solution
• NCBI GENE nr
  24392
• GENE symbol
  Gja1
• Antigene name
  gap junction protein, alpha 1
• Source
  Rattus norvegicus
• Protein nr
  P08050
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Connexin  
• Gene symbol
  GJA4, GJA3
• Short name
  anti-Connexin Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toConnexin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4278
• Gene
  GJA4
• Long gene name
  gap junction protein alpha 4
• Synonyms gene name
  • gap junction protein, alpha 4, 37kD (connexin 37)
  • gap junction protein, alpha 4, 37kDa (connexin 37)
  • gap junction protein, alpha 4, 37kDa
• Synonyms
  • CX37
• Synonyms name
  • connexin 37
• GenBank acession
  • M96789
• Locus
  1p34.3
• Discovery year
  1991-07-11
• Entrez gene record
  2701
• Pubmed identfication
  • 9843209
  • 7680674
• RefSeq identity
  • NM_002060
• Classification
  • Gap junction proteins
• VEGA ID
  OTTHUMG00000004050

Gene info

• Identity
  HGNC:4277
• Gene
  GJA3
• Long gene name
  gap junction protein alpha 3
• Synonyms gene
  • CZP3
• Synonyms gene name
  • gap junction protein, alpha 3, 46kD (connexin 46)
  • gap junction protein, alpha 3, 46kDa (connexin 46)
  • gap junction protein, alpha 3, 46kDa
• Synonyms
  • CX46
• Synonyms name
  • connexin 46
• GenBank acession
  • AF075290
• Locus
  13q12.11
• Discovery year
  1990-02-12
• Entrez gene record
  2700
• Pubmed identfication
  • 10205266
  • 7342922
• RefSeq identity
  • NM_021954
• Classification
  • Gap junction proteins
• VEGA ID
  OTTHUMG00000016510

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products