GSK-121 trifluoroacetate

• Catalog number
  B1034-500
• Price
  Please ask
• Size
  500 ug

• Alternative_name
  (3-​amino-1-​piperidinyl)​[1-​methyl-​2-​(1-​methyl-​1H-​indol-​2-​yl)​-​1H-​benzimidazol-​5-​yl]​-methanone, 2,​2,​2-​trifluoroacetate
• Description
  GSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor. GSK-121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC₅₀ value of 3.2 µM.
• CAS Number
  1652591-80-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₅N₅O •CF₃COOH
• Molecular Weight
  501.5
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (~30 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A novel protein arginine deiminase 4 (PAD4) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  O=C(N1CC(N)CCC1)C2=CC=C3N(C)C(C(N4C)=CC5=C4C=CC=C5)=NC3=C2.OC(C(F)(F)F)=O
• InChi
  InChI=1S/C23H25N5O.C2HF3O2/c1-26-19-8-4-3-6-15(19)13-21(26)22-25-18-12-16(9-10-20(18)27(22)2)23(29)28-11-5-7-17(24)14-28;3-2(4,5)1(6)7/h3-4,6,8-10,12-13,17H,5,7,11,14,24H2,1-2H3;(H,6,7)
• InChi Key
  CUCLWQZRCAQPJM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GSK-121   trifluoroacetate  
• Gene symbol
  TPRKB, SNORD4A, RNVU1-15
• Short name
  GSK-121 trifluoroacetate
• Alternative name
  GSK-121 trifluoroacetate

Gene info

• Identity
  HGNC:24259
• Gene
  TPRKB
• Long gene name
  TP53RK binding protein
• Synonyms
  • CGI-121
  • CGI121
• GenBank acession
  • AY157986
• Locus
  2p13.1
• Discovery year
  2006-02-02
• Entrez gene record
  51002
• Pubmed identfication
  • 10810093
  • 12659830
• RefSeq identity
  • NM_016058
• Classification
  • KEOPS complex
• VEGA ID
  OTTHUMG00000129815

Gene info

• Identity
  HGNC:10097
• Gene
  SNORD4A
• Long gene name
  small nucleolar RNA, C/D box 4A
• Synonyms gene
  • RNU101A
• Synonyms gene name
  • RNA, U101A small nucleolar
• Synonyms
  • Z17A
  • mgh18S-121
• GenBank acession
  • AJ224024
• Locus
  17q11
• Discovery year
  1999-12-14
• Entrez gene record
  26773
• Pubmed identfication
  • 9417910
• RefSeq identity
  • NR_000010
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:48320
• Gene
  RNVU1-15
• Long gene name
  RNA, variant U1 small nuclear 15
• Synonyms gene
  • RNVU1-16
• Synonyms gene name
  • RNA, variant U1 small nuclear 16
• Synonyms
  • vU1.15
  • RNU1-66
  • vU1.16
  • RNU1-121
• Locus
  1q21.2
• Discovery year
  2013-04-25
• Entrez gene record
  101954267
• Pubmed identfication
  • 23070852
• RefSeq identity
  • NR_104076
• Classification
  • Variant U1 small nuclear RNAs

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