HDAC3 Antibody
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Catalog number3603-100
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PricePlease ask
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Size100 µg
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Antibody TargetHDAC3
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Target Alternative NameSMAP45 , HD3 , RPD3 , RPD3-2
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat, chicken
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Immunogen SequenceSynthetic peptide corresponding to the C-terminus of human HDAC-3
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AccessionNP_003874
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Gene Id8841
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AppearanceColorless liquid
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FormLiquid
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Concentration0.2 mg/ml
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Formulation100 µg (0.2 mg/ml) peptide affinity purified rabbit anti-HDAC3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot, Immunohistochemistry
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Application And UsagesWestern blotting (0.5-4 µg/ml)and Immunohistochemistry (20-30 µg/ml). However, the optimal conditions should be determined individually.The antibody detects the 49 kDa HDAC3. It does not cross-react with other HDAC proteins including HDAC1, 2, 4, 5, 6, 7, and 8. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control.
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DescriptionHDAC3 is a member of the class I mammalian histone deacetylase family, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC3 is composed of 428 amino acid residues. HDAC3 interacts with a growing number of transcriptional factors including SMRT and N-CoR. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHDAC3
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Short nameHDAC3 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namehistone deacetylase 3 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targethistone deacetylase 3, HD3 and RPD3 and RPD3-2, HDAC3 and IDBG-50725 and ENSG00000171720 and 8841, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac3 and IDBG-140814 and ENSMUSG00000024454 and 15183, HDAC3 and IDBG-646121 and ENSBTAG00000017360 and 404125
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Gene info
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Identity
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Gene
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Long gene namehistone deacetylase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NCoR/SMRT transcriptional repression complex subunits
- Histone deacetylases, class I
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data