Radicicol

• Catalog number
  B1533-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  KF9-A, KF58332, Monorden, NSC 294404
• Description
  Radicicol is an antifungal antibiotic that inhibits heat shock protein 90 (Hsp90) activity by binding to the ATP-binding pocket, subsequently suppressing cell transformation induced by src, ras and mos. Represses estrogen receptor transcriptional activity and inhibits angiogenesis. Radicicol also binds to and inhibits DNA topoisomerase type II proteins and GRP94 through an ATPase domain common to Hsp90.
• CAS Number
  12772-57-5
• Structure Available
  Yes
• Molecular Formula
  C₁₈H₁₇ClO₆
• Molecular Weight
  364.78
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  An antifungal antibiotic and heat shock protein 90 (Hsp90) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD06795865
• PubChem CID
  6323491
• PubChem CID Link
• SMILES
  CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1
• InChi
  InChI=1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3-/t9-,14-,15-/m1/s1
• InChi Key
  WYZWZEOGROVVHK-GTMNPGAYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Radicicol  
• Short name
  Radicicol
• Alternative name
  Radicicol

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