Heregulin-β2 (HRG2β), Human Recombinant

• Catalog number
  4730-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Heregulin-β2 (HRG2β), Human Recombinant
• Alternative_names
  Neuregulin-1, NRG1, GGF, HGL, HRGA, NDF, SMDF, HRG, ARIA, GGF2, HRG1
• Description
  A signaling protein for ErbB2/ErbB4 receptor
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Purity
  ≥95%
• Molecular Weight
  7.4 kDa (65 aa, 177-237)
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from water.
• Background Information
  Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG-β2 is a signaling protein for ErbB2/ErbB4 receptor on the cardiac muscle cells. The polypeptide is comprised of an immunoglobulin and epidermal growth factor-like (EGF-like) domains.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Heregulin-β2   HRG2β  
• Gene symbol
  NRG2
• Short name
  Heregulin-β2 (HRG2β), Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  Heregulin-β2 (HRG2β), H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:7998
• Gene
  NRG2
• Long gene name
  neuregulin 2
• Synonyms
  • Don-1
  • NTAK
  • HRG2
• Synonyms name
  • neural- and thymus-derived activator for ErbB kinases
  • divergent of neuregulin-1
• Locus
  5q31.2
• Discovery year
  1999-03-19
• Entrez gene record
  9542
• Pubmed identfication
  • 9168114
  • 9168115
• RefSeq identity
  • NM_013982
• Classification
  • Neuregulins
  • I-set domain containing
• VEGA ID
  OTTHUMG00000129241

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products