Briciclib

• Catalog number
  B1140-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
• Description
  Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells. Cyclin D, a member of the cyclin family of cell cycle regulators, plays a key role in cell cycle division and is often overexpressed in a variety of hematologic and solid tumors and is correlated with poor prognosis.
• CAS Number
  865783-99-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₂₃O₁₀PS
• Molecular Weight
  474.42
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A suppressor cyclin D1 accumulation in cancer cells
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11248490
• PubChem CID Link
• SMILES
  COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
• InChi
  1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
• InChi Key
  LXENKEWVEVKKGV-BQYQJAHWSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Briciclib  
• Short name
  Briciclib
• Alternative name
  Briciclib

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