Recombinant Human Fc γ RIIIB/FCGR3B/CD16b Protein(C-Fc-6His) 50µg
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Catalog number
PKSH032421-50µg
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Price
Please ask
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Size
50µg
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Synonym
Low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B.
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Activity
NA
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Sequence
Thr20-Gln208
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Fusion tag
C-Fc-6His
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Accession
O75015
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Expressed Host
Human cells
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Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity
＞95% as determined by reducing SDS-PAGE.
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Endotoxin
＜1.0 EU per µg as determined by LAL test.
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Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass
41.7 kDa
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AP Mol Mass
70 kDa
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Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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Reconstitution
Please refer to it for detailed information.
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Background
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FCGR3B
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Short name
Recombinant Fc γ RIIIB/FCGR3B/CD16b Protein(C-Fc-6His) 50µg
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Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Rec. H. sapiens fragment c γ RIIIB/fragment c fragment on Immunoglobulin G, low affinity IIIb, receptor (CD16b)/CD16b Protein(C-fragment c-6His) 50µg
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Alternative technique
rec
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Alternative to gene target
Fc fragment of IgG, low affinity IIIb, receptor (CD16b), CD16 and CD16b and FCG3 and FCGR3 and FCR-10 and FCRIII and FCRIIIb, FCGR3B and IDBG-104303 and ENSG00000162747 and 2215, IgG binding, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene name
Fc gamma receptor IIIb
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
- Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
- Fc fragment of IgG receptor IIIb
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Synonyms
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GenBank acession
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Locus
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Discovery year
1991-08-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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