Histone H4 Antibody

  • Catalog number
    F52511-0.08ML
  • Price
    Please ask
  • Size
    0.08 ml
  • Category
    Antibody
  • Concentration
    In 1X PBS pH 7.4 with 0.09% sodium azide
  • Form
    Antigen affinity purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    Histone H4
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, FACS, IHC, ELISA
  • Recommended dilutions
    Flow Cytometry: 1:25,IHC (Paraffin): 1:25,Western blot: 1:1000
  • Notes
    Titration of the Histone H4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This Histone H4 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P62805
  • Purity
    Antigen affinity
  • Description
    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  • Immunogen
    This Histone H4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 71-103 amino acids from the C-terminal region of human HIST1H4A.
  • Storage
    Aliquot the Histone H4 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Histone  
  • Gene symbol
    H4-16, H4C8, H4C14
  • Short name
    Anti-Histone H4
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit Ig
  • Alternative name
    Antibodies to Histone H4
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    H4 clustered histone 8
  • Synonyms gene
  • Synonyms gene name
    • H4 histone family, member H
    • histone 1, H4h
    • histone cluster 1, H4h
    • histone cluster 1 H4 family member h
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-09-07
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • H4 histones
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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