KRIBB11

• Catalog number
  B1567-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine
• Description
  KRIBB11 is a Heat shock factor (HSF) inhibitor (IC₅₀ = 1.2 μM). KRIBB11 blocks the induction of HSF1 downstream target proteins such as HSP27 and HSP70. KRIBB11 induces growth arrest and apoptosis of HCT-116 cells.
• CAS Number
  342639-96-7
• Molecular Formula
  C₁₃H₁₂N₆O₂
• Molecular Weight
  284.28
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A Heat shock factor (HSF) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  69894253
• PubChem CID Link
• SMILES
  CNC1=NC(=C(C=C1)[N+](=O)[O-])NC2=CC3=C(C=C2)NN=C3
• InChi
  InChI=1S/C13H12N6O2/c1-14-12-5-4-11(19(20)21)13(17-12)16-9-2-3-10-8(6-9)7-15-18-10/h2-7H,1H3,(H,15,18)(H2,14,16,17)
• InChi Key
  NDJJEQIMIJJCLL-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  KRIBB11  
• Short name
  KRIBB11
• Alternative name
  KRIBB11

Similar products