KRIBB11
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Catalog numberB1567-5
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Price:
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Size5 mg
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Alternative_nameN2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine
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DescriptionKRIBB11 is a Heat shock factor (HSF) inhibitor (IC₅₀ = 1.2 μM). KRIBB11 blocks the induction of HSF1 downstream target proteins such as HSP27 and HSP70. KRIBB11 induces growth arrest and apoptosis of HCT-116 cells.
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CAS Number342639-96-7
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Molecular FormulaC₁₃H₁₂N₆O₂
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Molecular Weight284.28
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>25 mg/ml)
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HandlingProtect from air and light
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Tag LineA Heat shock factor (HSF) inhibitor
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID69894253
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SMILESCNC1=NC(=C(C=C1)[N+](=O)[O-])NC2=CC3=C(C=C2)NN=C3
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InChiInChI=1S/C13H12N6O2/c1-14-12-5-4-11(19(20)21)13(17-12)16-9-2-3-10-8(6-9)7-15-18-10/h2-7H,1H3,(H,15,18)(H2,14,16,17)
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InChi KeyNDJJEQIMIJJCLL-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameKRIBB11
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Alternative nameKRIBB11
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