GalNAc-T16, soluble fragment, Human Recombinant
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Catalog number
P1218-5
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Price
Please ask
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Size
5 ug
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Synonyms
Polypeptide N-acetylgalactosaminyltransferase, Protein-UDP acetylgalactosaminyltransferase, GALNTL1, GALNT16
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Alternative_names
Polypeptide N-acetylgalactosaminyltransferase, Protein-UDP acetylgalactosaminyltransferase, GALNTL1, GALNT16
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Description
Involved in the pathway protein glycosylation
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Recombinant
Yes
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Source
Insect cells
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Purity by SDS PAGE
> 90%
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Assay
SDS-PAGE
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Concentration
100 ug/ml
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Appearance
Liquid
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Physical form description
Sterile filtered solution in 25 mM Tris pH 7.5 and 150 mM NaCl
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Background Information
Polypeptide N-acetylgalactosaminyltransferase 16 (GalNAc-T16) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty GalNAc-T genes have been identified in humans and most have been shown to represent active GalNAc-Ts. All isoforms are type II transmembrane proteins, with different but partly overlapping substrate preferences. The GalNAc-Ts control the initiation of mucin-type O-linked glycosylation and determine the location and density of O-glycans in a protein. Addition of GalNAc to an unglycosylated Ser/Thr residue creates the Tn antigen GalNAcα1-S/T, and subsequent addition of sialic acid by ST6GalNAc-I forms the cancer associated STn antigen.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
GALNT16
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Short name
GalNAc-T16, soluble , Recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Isotype
Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
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Species
Human, Humans
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Alternative name
GalNAc-T16, soluble fragment, H. sapiens Rec.
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Alternative technique
rec
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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