Caspase-4 Substrate LEVD-pNA
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Catalog number
1110-200
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Price
Please ask
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Size
200 assays
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Alternative_name
Ac-LEVD-pNA, Caspase-4 Substrate, Colorimetric
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Description
Ready-to-use colorimetric substrate for caspase-4 and related caspases that recognize the amino acid sequence LEVD. Caspase-4 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate LEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for large volume users.
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Structure Available
No
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Peptide sequence
Ac- Leu-Glu-Val-Asp-pNA
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Salt Form
No
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Molecular Formula
C₂₈H₄₀N₆O₁₁
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Molecular Weight
636.65
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Cell Permeable
No
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Purity
>98% by HPLC
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Handling
Protect from light and moisture
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Tag Line
A caspase-4 substrate
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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PubChem CID
44135314
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SMILES
CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C
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InChi
InChI=1S/C28H40N6O11/c1-14(2)12-20(29-16(5)35)27(42)31-19(10-11-22(36)37)25(40)33-24(15(3)4)28(43)32-21(13-23(38)39)26(41)30-17-6-8-18(9-7-17)34(44)45/h6-9,14-15,19-21,24H,10-13H2,1-5H3,(H,29,35)(H,30,41)(H,31, 42)(H,32,43)(H,33,40)(H,36,37)(H,38,39)
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InChi Key
KNKMVACCCNFUDD-UHFFFAOYSA-N
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MSDS Available
Yes
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
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