Cathepsin C/DPP1 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-2672R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  Cathepsin C/DPP1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-Cathepsin C/DPP1 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Cathepsin C/DPP1
• Specificity
  This is a highly specific antibody against Cathepsin C/DPP1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DPP-I
• Gene ID Number
  1075
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Dipeptidyl peptidase I; AI047818; CATC; Cathepsin C; Cathepsin J; CPPI; CTSC; Dipeptidyl peptidase 1; Dipeptidyl transferase; DPP I; DPPI; EC 3.4.14.1; HMS; JP; JPD; MGC126959; PALS; PLS.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Cathepsin C/DPP1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• Gene
  CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
• French translation
  anticorps

• Gene target
  Cathepsin   C/DPP1  
• Gene symbol
  CTSC
• Short name
  Anti-Cathepsin C/DPP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  Cathepsin C/DPP1 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2528
• Gene
  CTSC
• Long gene name
  cathepsin C
• Synonyms gene
  • PLS
  • PALS
• Synonyms
  • DPP1
• Synonyms name
  • dipeptidyl peptidase 1
• GenBank acession
  • AK223038
• Locus
  11q14.2
• Discovery year
  1995-11-08
• Entrez gene record
  1075
• Pubmed identfication
  • 7649281
  • 9092576
• RefSeq identity
  • NM_001814
• Classification
  • Cathepsins
• VEGA ID
  OTTHUMG00000167290
• Locus Specific Databases
  • CTSCbase: Mutation registry for Papillon-Lefevre syndrome
  • LRG_50

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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