BioSim™ anti-VEGF-A (Human) ELISA Kit
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Catalog number
E4312-100
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Price
Please ask
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Size
100 assays
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Description
A Sandwich ELISA kit for the quantitative measurement of Ranibizumad in serum, plasma, culture supernatants and other biological fluids.
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Summary
• Detection method- Absorbance (450 nm) • Species reactivity- Human • Application- quantitative measurement of Ranibizumad in human serum and plasma
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Detection Method
Absorbance (450 nm)
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Species Reactivity
Human
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Applications
Quantitative measurement of Ranibizumad in human serum and plasma
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Sample Type
Human serum and plasma
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Features Benefits
Easy, convenient, sensitive and time-saving method to measure the level of Ranibizumad in human serum and plasma. Detection Range: 1.22 – 625 ng/ml
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Storage Conditions
-20°C
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Shipping Conditions
gel pack
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Shelf life
12 months
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Background
Ranibizumab (Lucentis®) is a recombinant human IgG1 monoclonal antibody fragment (Fab) that blocks angiogenesis by inhibiting vascular endothelial growth factor-A (VEGF-A) isoforms. The humanized anti-VEGF monoclonal antibody, Ranibizumab, has been approved by the FDA for treatment of patients with wet age-related macular degeneration. Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people over the age of 50 in the developed world. Although an estimated 80% of patients with AMD have the non-neo vascular form, the neo vascular (wet or exudative) form is responsible for almost 90% of severe visual loss resulting from AMD. Currently, the most commonly used VEGF antagonists are ranibizumab (Lucentis, Genentech, Inc.) and Ranibizumab (Avastin; Genentech, Inc.). Ranibizumab, which is an antibody fragment form the Ranibizumab molecule with an increased binding affinity for all forms of VEGF, has been approved for the treatment of patients with neo-vascular AMD by the Food and Drug Administration and by the European Medicines Agency. BioVision’s Ranibizumab ELISA kit is developed for the quantification of Ranibizumab concentration in human serum or plasma with high sensitivity and reproducibility.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays, E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays, Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED
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Gene target
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Gene symbol
VEGFA, VEGFD, VEGFC, HLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1
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Short name
BioSim™ anti-VEGF-A ( ) ELISA Kit
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Technique
ELISA kit, anti-, ELISA, anti, antibody to, antibodies, ELISAs Enzyme-linked immunosorbent assay 90320007 SNOMED code are used by the medical researcher for detection of human, mouse, … proteins are supplied in coated 96 well plates to be stored at +4°C. ELISA test kits can be sandwich ELISA. In sandwich ELISAS Enzyme-linked immunosorbent assay 9we use captor and detector antibodies. In single antibody ELISAs the antigen is coated and only a detector antibody is used. Traditional competition antigen ELISAs are coated with a captor antibody and a competitive antigen is labelled with the chromogen. In this case the ratio on your graph will be inverse proportional with the antigen present in your sample. A sign detected by the Colorimetric detection OD optical density absorbance at 450 nm between 0 and 4 with an ELISA reader for 450 nm absortion. Genprice Inc. the recognized authority tax ID 45-4304622 D-U-N-S number - 078440800. MeSH code E05 478 566 350 170 Enzyme-Linked Immunosorbent Assay. PROMT code 3841327 Immunoabsorbent assay tests. ELISA tests are enzyme linked immunoassays to detect human, mouse or other proteins in serum, plasma, urine or biological fluids. MeSH code E05 478 566 350 170 for Enzyme-Linked Immunosorbent Assay or ELISA kits. Also Enzyme-linked immunoassay, competitive have the SNOMED name 61461007 and the PROMT code for ELISA readers is 3841330. This is the desigation of other diagnostic analyzers and tests.
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Host
antigen assay ELISA kit 1 Kit (96 Wells)
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Species
Humans
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Alternative name
BioSim™ Antibody toVEGF-A (H. sapiens) Enzyme-linked immunosorbent assay reagent
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Alternative technique
antibodies, elisas, kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
replication protein A1
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Synonyms gene name
- replication protein A1 (70kD)
- replication protein A1, 70kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year
1993-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
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VEGA ID
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
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Tree numbers
- E05.478.566.350.170
- E05.478.566.380.360
- E05.478.583.400.170
- E05.601.470.350.170
- E05.601.470.380.360
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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