PTH 1-84/Parathyroid hormone/Parathormone
-
Catalog numberE21-010
-
PricePlease ask
-
Size10ug
-
-
Shipping_TemperatureAmbient
-
Product_StateLyophilized
-
Formulation_DescriptionLyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.
-
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
-
PurityGreater than 95% as determined by reducing SDS-PAGE.
-
EndotoxinLess than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
-
BackgroundParathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.
-
Alternative NamesParathyroid Hormone; PTH; Parathormone; Parathyrin
-
Expression systemE.coli
-
DescriptionHormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.
-
Gene target
-
Gene symbolPTH, SPAG8, GOLGA5, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, ERGIC3, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1
-
Short namePTH 1-84/Parathyroid hormone/Parathormone
-
SpeciesHuman
-
Alternative nameparathyroid hormone 1-84/Parathyroid hormone/Parathormone
-
Alternative to gene targetparathyroid hormone, PTH1, PTH and IDBG-32891 and ENSG00000152266 and 5741, peptide hormone receptor binding, Extracellular, Pth and IDBG-207092 and ENSMUSG00000059077 and 19226, PTH and IDBG-632953 and ENSBTAG00000019080 and 280903
-
Gene info
-
Identity
-
Gene
-
Long gene nameparathyroid hormone
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesperm associated antigen 8
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-01-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namegolgin A5
-
Synonyms gene name
- golgi autoantigen, golgin subfamily a, 5
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-04-28
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Golgins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
-
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-17
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1/206 family
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 8-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
Gene info
-
Identity
-
Gene
-
Long gene nameERGIC and golgi 3
-
Synonyms gene
-
Synonyms gene name
- serologically defined breast cancer antigen 84
- chromosome 20 open reading frame 47
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-07-31
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 7-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
-
Synonyms gene
-
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Immunoglobulin kappa (IGK) orphons
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 101-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR101 family