Rabbit anti Phosphodiesterase 9A (PDE9A)
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Catalog number
X2280P
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Price
Please ask
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Size
50 μg
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Category
Primary Antibodies
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Long description
Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.
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Antibody come from
Synthetic peptide derived from the human ACAD11 protein
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Other description
Provided as solution in phosphate buffered saline. Immunoaffinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Phosphodiesterase 9A (PDE9A) Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Immunohistochemistry
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Antibody s suited for
For use with ACAD11 polyclonal antibodies (Cat. No. X2086P & X2319P).
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Storage
Long term: -70ºC; Short term: +4ºC
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Relevant references
1. He, M, et al. Identification and characterization of new long chain acyl-CoA dehydrogenases. Mol. Genet. Metab. 2011, 102, 418-429
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
PDE9A, PDE9A-AS1
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Short name
Rabbit anti Phosphodiesterase 9A (PDE9A)
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Technique
Rabbit, anti, antibody to
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Host
Rabbit, Rabbits
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Isotype
not specified
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Label
unlabeled
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Alternative name
production species: rabbit antibody to Phosphodiesterase 9A (PDE9A)
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Alternative technique
rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene name
phosphodiesterase 9A
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GenBank acession
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Locus
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Discovery year
1998-06-12
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
PDE9A antisense RNA 1
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Locus
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Discovery year
2019-09-19
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Entrez gene record
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Classification
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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