Anti-UHRF1 Antibody (1H9-D3-E11)
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Catalog numberA1319-100
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PricePlease ask
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Size100 µg
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Antibody TargetUHRF1
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Target Alternative NameE3 ubiquitin-protein ligase UHRF1, Inverted CCAAT box-binding protein of 90 kDa, Nuclear protein 95, Nuclear zinc finger protein Np95, HuNp95, hNp95, RING finger protein 106, FLJ21925, ICBP90, mgC138707, Np95, RNF106, hNP95
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Antibody TypeMonoclonal
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Clone1H9-D3-E11
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Species ReactivitiesHuman
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Immunogen SequenceRecombinant human UHRF1 protein fragments expressed in E.coli
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AccessionQ96T88
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Gene Id29128
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AppearanceColorless liquid
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FormLiquid
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FormulationIn buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
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PurificationAffinity purified
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ApplicationWB
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Positive ControlWB: Mouse heart, 293T, HeLa nuclear extract and HeLa cell lysates
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Application And UsagesWB; 1:1000
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DescriptionMultidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication. In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans
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HandlingThe antibody solution should be gently mixed before use
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSNRPD3, NCAPD3, TRO, UHRF1
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Short nameAnti-UHRF1 Antibody (1H9-D3-E11)
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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IsotypeMouse IgG2b
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Alternative nameAntibody toUHRF1 (antibody to-) (1H9-D3-E11)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namesmall nuclear ribonucleoprotein D3 polypeptide
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Synonyms gene name
- small nuclear ribonucleoprotein D3 polypeptide (18kD)
- small nuclear ribonucleoprotein D3 polypeptide 18kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-04-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sm spliceosomal proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenon-SMC condensin II complex subunit D3
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Synonyms gene name
- non-SMC condensin II complex, subunit D3
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-09-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Condensin II subunits
- Armadillo like helical domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametrophinin
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-10-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
- Small nucleolar RNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameubiquitin like with PHD and ring finger domains 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-03-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Ring finger proteins
- PHD finger proteins
- Tudor domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data