HP1α, ß and γ polyclonal antibody
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Catalog number6861-25
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Price:
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Size25 μg
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Antibody TargetHP1α, ß and γ
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Target Alternative NameCBX5, 1, 3
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse.
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Immunogen SequencePolyclonal antibody raised in rabbit against human HP1 β (Heterochromatin protein 1 homolog beta), using the full length recombinant GST tagged protein. The antibody also recognizes the α and γ isoforms.
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AccessionP45973, P83916, Q13185
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Gene Id23468, 10951, 11335
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AppearanceColorless liquid
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FormLiquid
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FormulationIn PBS with 0.05% sodium azide and 0.05% ProClin 300.
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PurificationProtein G purified
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ApplicationWestern blot, IF, ChIP.
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Positive ControlChIP: NIH 3T3 cells, Western blot: HeLa cells, IF: HeLa cells.
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Application And UsagesWestern Blot: 1:1000, IF: 1:500, ChIP: 4 µg/ChIP
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DescriptionHP1 alpha, beta and gamma are components of heterochromatin. They recognize and bind histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the inner nuclear membrane.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedVerified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedVerified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translationanticorps
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Gene target
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Gene symbolCBX5, HP1BP3, CBX1, TFF1
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Short nameHP1α, ß γ polyclonal antibody
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TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeRabbit IgG
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Alternative nameHP1α, ß and γ polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene namechromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheterochromatin protein 1 binding protein 3
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Synonyms gene name
- heterochromatin protein 1, binding protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-05-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromobox 1
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Synonyms gene name
- chromobox homolog 1 (Drosophila HP1 beta)
- chromobox homolog 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametrefoil factor 1
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Synonyms gene
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Synonyms gene name
- breast cancer, estrogen-inducible sequence expressed in
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data