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PKC412 for cell activation

PKC412 for cell activation is available 0 time from Biovision labs

Description Cell-permeable. A derivative of Staurosporine (Cat. No. 1048) that inhibits a variety of serine/threonine and tyrosine kinases including protein kinase C (PKC) IC₅₀ = 50 nM), cyclic AMP-dependent protein kinase (PKA) (IC₅₀ = 2.4 µM), S6 kinase (IC₅₀ = 5.0 µM), and EGFR (IC₅₀ = 3.0 µM). PKC412 reverses the efflux function of the multidrug resistance (MDR)-1 gene product, P-glycoprotein (P-gp).
Peptide sequence N/A
CAS number 120685-11-2
Molecular weight 570.64
Category Biochemicals
Other name 4'-N-Benzoyl Staurosporine; CGP-41251; Midostaurin
Molecular formula C₃₅H₃₀N₄O₄
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥99% by HPLC
Reconstitute instructions DMSO (~ 10 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 24 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetPKC412 for activation
Short name PKC412 for activation
Technique activation
Alternative name PKC412 to measure cellular activation
Tissue cell
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PKC412 for cell activation -
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • PKC412
  • for
  • activation
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