anti- HNMT antibody
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Catalog numberFNab03944
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PricePlease ask
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Size2X100μg
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Formliquid
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PurificationImmunogen affinity purified
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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BackgroundIn mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
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Immunogenhistamine N-methyltransferase
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Calculated MW27 kDa
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Uniprot IDP50135
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SpecificityHuman, Mouse
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Tested ApplicationELISA, WB, IHC, IP
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Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:20 - 1:50
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Image1Immunohistochemistry of paraffin-embedded human lymphoma using FNab03944(HNMT antibody) at dilution of 1:50
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Image4human liver tissue were subjected to SDS PAGE followed by western blot with FNab03944(HNMT antibody) at dilution of 1:1000
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHNMT
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Short nameanti- HNMT antibody
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit
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IsotypeIgG
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Alternative nameantibody to- histamine N-methyltransferase (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targethistamine N-methyltransferase, HMT and HNMT-S1 and HNMT-S2, HNMT and IDBG-71109 and ENSG00000150540 and 3176, histamine N-methyltransferase activity, nuclei, Hnmt and IDBG-141972 and ENSMUSG00000026986 and 140483, HNMT and IDBG-642173 and ENSBTAG00000014432 and 613413
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Gene info
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Identity
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Gene
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Long gene namehistamine N-methyltransferase
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Locus
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Discovery year1994-04-18
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Entrez gene record
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Classification
- 7BS small molecule methyltransferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data