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Long name
KCNA2B/Kv beta 2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
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Also known as
Anti-KCNA2B/Kv beta 2 PAb ALEXA FLUOR 488
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 488
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
KCNA2B/Kv beta 2
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Specificity
This is a highly specific antibody against KCNA2B/Kv beta 2.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNA2B/Kv beta 2
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming a-subunits (KV), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. Differences exist in the patterns of trafficking, biosynthetic processing, and surface expression of the major KV1 subunits (KV1.1, KV1.2, and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels. KV beta.2 can also be designated KCNAB2, KKv beta2.1 or AKR6A5.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
499nm/519nm
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Synonyms
AKR6A5; HKv beta 2; HKvbeta 2; HKvbeta2.1; HKvbeta2.2; K+ channel subunit beta 2; K+ channel beta 2 subunit; KCNA2B; KCNAB 2; KCNAB2; KCNK2; Kv Beta 2; Kvbeta2; MGC117289; Potassium channel shaker chain beta 2; Potassium voltage gated channel shaker related subfamily; Potassium voltage gated channel shaker related subfamily beta member 2; Voltage gated potassium channel beta 2 subunit; Voltage gated potassium channel subunit beta 2;
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-KCNA2B/Kv beta 2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor
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French translation
anticorps