GSK-2110183

• Catalog number
  B1089-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
• Description
  GSK-2110183 is a potent, selective, and ATP-competitive pan-Akt inhibitor with IC₅₀s of 0.08, 2 and 2.6 nM for Akt1, Akt2, and Akt3 respectively.
• CAS Number
  1047644-62-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₇Cl₂FN₄OS
• Molecular Weight
  427.32
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, selective, and ATP-competitive pan-Akt inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  46843057
• PubChem CID Link
• SMILES
  CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)NC(CC3=CC(=CC=C3)F)CN)Cl
• InChi
  InChI=1S/C18H17Cl2FN4OS/c1-25-16(14(19)9-23-25)13-7-15(27-17(13)20)18(26)24-12(8-22)6-10-3-2-4-11(21)5-10/h2-5,7,9,12H,6,8,22H2,1H3,(H,24,26)/t12-/m0/s1
• InChi Key
  AFJRDFWMXUECEW-LBPRGKRZSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GSK-2110183  
• Short name
  GSK-2110183
• Alternative name
  GSK-2110183

Product images

Similar products